Peroxisome Proliferator-Activated Receptors and Hepatitis C Virus-Induced Insulin Resistance
Author
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-01-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Insulin resistance and type 2 diabetes are associated with hepatitis C virus infection.
A wealth of clinical and experimental data suggests that the virus is directly interfering with the insulin signalling in hepatocytes.
In the case of at least one viral genotype (the type 3a), insulin resistance seems to be directly mediated by the downregulation of the peroxisome proliferator-activated receptor γ.
Whether and how this interaction may be manipulated pharmacologically, in order to improve the responsiveness to antivirals of insulin resistant chronic hepatitis C, patients remain to be fully explored.
American Psychological Association (APA)
Negro, Francesco. 2009. Peroxisome Proliferator-Activated Receptors and Hepatitis C Virus-Induced Insulin Resistance. PPAR Research،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-475203
Modern Language Association (MLA)
Negro, Francesco. Peroxisome Proliferator-Activated Receptors and Hepatitis C Virus-Induced Insulin Resistance. PPAR Research No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-475203
American Medical Association (AMA)
Negro, Francesco. Peroxisome Proliferator-Activated Receptors and Hepatitis C Virus-Induced Insulin Resistance. PPAR Research. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-475203
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475203