A Case of Thrombotic Thrombocytopenia Purpura Associated with Systemic Lupus Erythematosus : Diagnostic Utility of ADAMTS-13 Activity
Joint Authors
Takamori, Kenji
Sekigawa, Iwao
Yamada, Risa
Takasaki, Yoshinari
Yoshimine, Takashi
Nozawa, Kazuhisa
Ogawa, Hideoki
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Thrombotic thrombocytopenia purpura (TTP) caused by a deficiency in ADAMTS-13 activity is considered to involve a subset of thrombotic microangiopathy (TMA).
Although concept of TTP is included under the umbrella of TMA, discrimination of TTP from TMA is occasionally difficult in an autoimmune disorder.
Herein, we report a case with TTP associated with systemic lupus erythematosus (SLE).
In this case, it was difficult to discriminate TTP from TMA and the measurement of ADAMTS-13 activity was useful for obtaining an accurate diagnosis.
SLE patients having thrombocytopenia in complication with anemia should be considered a monitoring of ADAMTS-13 activity even though the patients lacked symptoms of TTP related to the microvascular coagulation.
American Psychological Association (APA)
Yamada, Risa& Nozawa, Kazuhisa& Yoshimine, Takashi& Takasaki, Yoshinari& Ogawa, Hideoki& Takamori, Kenji…[et al.]. 2011. A Case of Thrombotic Thrombocytopenia Purpura Associated with Systemic Lupus Erythematosus : Diagnostic Utility of ADAMTS-13 Activity. Autoimmune Diseases،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-475221
Modern Language Association (MLA)
Yamada, Risa…[et al.]. A Case of Thrombotic Thrombocytopenia Purpura Associated with Systemic Lupus Erythematosus : Diagnostic Utility of ADAMTS-13 Activity. Autoimmune Diseases No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-475221
American Medical Association (AMA)
Yamada, Risa& Nozawa, Kazuhisa& Yoshimine, Takashi& Takasaki, Yoshinari& Ogawa, Hideoki& Takamori, Kenji…[et al.]. A Case of Thrombotic Thrombocytopenia Purpura Associated with Systemic Lupus Erythematosus : Diagnostic Utility of ADAMTS-13 Activity. Autoimmune Diseases. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-475221
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475221