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Automated Measurement of Immature Granulocytes : Performance Characteristics and Utility in Routine Clinical Practice
Joint Authors
Rao K., Ramesh
Sukumaran, Jayapriya
Kumar, Treshul
Senthilnayagam, Balamurugan
Jeya M.
Source
Pathology Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The granulocytic “shift to left” reflects marrow response to bacterial infection, and this may be quantified as band count or immature granulocyte count (IGC).
The former value, used widely in neonatal sepsis, has been notoriously difficult to measure accurately and precisely.
A reproducible, precise, and accurate counting of immature granulocyte counts may be possible with automation.
This study of 200 febrile patients aimed at analysing the performance characteristics of automated immature granulocytes (AIGs) in predicting blood culture and their clinical utility.
The absolute (IGC) and relative IG count (IG%) had area under curve (AUC) of 0.69 and 0.66.
Moreover, the means of IGC and IG% between culture positive and negative groups were statistically significant suggesting that they are potential markers for bacteremia.
IGC of 0.03 × 103 cu⋅mm and IG% of 0.5% offered sensitivity of 86.3% and 92.2%, respectively, and may be used for screening for bacteremia.
Higher values, IGC > 0.3, and IG% > 3 had specificity greater than 90%, although the values were infrequent.
It may not be long before that these automated hemograms are put into regular diagnostic use.
American Psychological Association (APA)
Senthilnayagam, Balamurugan& Kumar, Treshul& Sukumaran, Jayapriya& Jeya M.& Rao K., Ramesh. 2012. Automated Measurement of Immature Granulocytes : Performance Characteristics and Utility in Routine Clinical Practice. Pathology Research International،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-475226
Modern Language Association (MLA)
Senthilnayagam, Balamurugan…[et al.]. Automated Measurement of Immature Granulocytes : Performance Characteristics and Utility in Routine Clinical Practice. Pathology Research International No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-475226
American Medical Association (AMA)
Senthilnayagam, Balamurugan& Kumar, Treshul& Sukumaran, Jayapriya& Jeya M.& Rao K., Ramesh. Automated Measurement of Immature Granulocytes : Performance Characteristics and Utility in Routine Clinical Practice. Pathology Research International. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-475226
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475226