The Risk of Acute Kidney Injury and Its Impact on 30-Day and Long-Term Mortality after Transcatheter Aortic Valve Implantation
Joint Authors
Reinecke, Holger
Gebauer, Katrin
Kerckhoff, Gregor
Meyborg, Matthias
Malyar, Nasser
Kaleschke, Gerrit
Baumgartner, Helmut
Diller, Gerhard-Paul
Source
International Journal of Nephrology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Transcatheter aortic valve implantation (TAVI) is widely used in high risk patients (pts) with aortic stenosis.
Underlying chronic kidney disease implicates a high risk of postprocedural acute kidney injury (AKI).
We analyzed its occurrence, impact on hospital stay, and mortality.
Methods.
150 consecutive pts underwent TAVI in our institution (mean age 81 ± 7 years; logistic EuroSCORE 24 ± 15%).
AKI definition was a creatinine rise of 26.5 μmol/L or more within 48 hours postprocedural.
Ten patients on chronic hemodialysis were excluded.
Results.
AKI occurred in 28 pts (20%).
Baseline creatinine was higher in AKI pts (126.4 ± 59.2 μmol/L versus 108.7 ± 45.1 μmol/L, P=0.09).
Contrast media use was distributed evenly.
Both, 30-day mortality (29% versus 7%, P<0.0001) and long-term mortality (43% versus 18%, P<0.0001) were higher; hospital stay was longer in AKI pts (20 ± 12 versus 15 ± 10 days, P=0.03).
Predicted renal failure calculated STS Score was similar (8.0 ± 5.0% [AKI] versus 7.1 ± 4.0% [non-AKI], P=0.32) and estimated lower renal failure rates than observed.
Conclusion.
AKI remains a frequent complication with increased mortality in TAVI pts.
Careful identification of risk factors and development of more suitable risk scores are essential.
American Psychological Association (APA)
Gebauer, Katrin& Diller, Gerhard-Paul& Kaleschke, Gerrit& Kerckhoff, Gregor& Malyar, Nasser& Meyborg, Matthias…[et al.]. 2012. The Risk of Acute Kidney Injury and Its Impact on 30-Day and Long-Term Mortality after Transcatheter Aortic Valve Implantation. International Journal of Nephrology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-475234
Modern Language Association (MLA)
Gebauer, Katrin…[et al.]. The Risk of Acute Kidney Injury and Its Impact on 30-Day and Long-Term Mortality after Transcatheter Aortic Valve Implantation. International Journal of Nephrology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-475234
American Medical Association (AMA)
Gebauer, Katrin& Diller, Gerhard-Paul& Kaleschke, Gerrit& Kerckhoff, Gregor& Malyar, Nasser& Meyborg, Matthias…[et al.]. The Risk of Acute Kidney Injury and Its Impact on 30-Day and Long-Term Mortality after Transcatheter Aortic Valve Implantation. International Journal of Nephrology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-475234
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475234