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Molecular Adaptation of Modern Human Populations
Joint Authors
Source
International Journal of Evolutionary Biology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Modern humans have gone through varied processes of genetic adaptations when their ancestors left Africa about 100,000 years ago.
The environmental stresses and the social transitions (e.g., emergence of the Neolithic culture) have been acting as the major selective forces reshaping the genetic make-up of human populations.
Genetic adaptations have occurred in many aspects of human life, including the adaptation to cold climate and high-altitude hypoxia, the improved ability of defending infectious diseases, and the polished strategy of utilizing new diet with the advent of agriculture.
At the same time, the adaptations once developed during evolution may sometimes generate deleterious effects (e.g., susceptibility to diseases) when facing new environmental and social changes.
The molecular (especially the genome-wide screening of genetic variations) studies in recent years have detected many genetic variants that show signals of Darwinian positive selection in modern human populations, which will not only provide a better understanding of human evolutionary history, but also help dissecting the genetic basis of human complex diseases.
American Psychological Association (APA)
Shi, Hong& Su, Bing. 2010. Molecular Adaptation of Modern Human Populations. International Journal of Evolutionary Biology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-475322
Modern Language Association (MLA)
Shi, Hong& Su, Bing. Molecular Adaptation of Modern Human Populations. International Journal of Evolutionary Biology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-475322
American Medical Association (AMA)
Shi, Hong& Su, Bing. Molecular Adaptation of Modern Human Populations. International Journal of Evolutionary Biology. 2010. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-475322
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475322