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The Immune Enhancement of Sodium Lauryl Sulfoacetate in Chickens
Joint Authors
Sun, HuaiChang
Cheng, DaRong
Zhu, ShanYuan
Source
Veterinary Medicine International
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The purpose of this study is to investigate feasibility of sodium lauryl sulfoacetate (SLS) as an immunoadjuvant in chickens.
After treating with 62.5, 125, 250, or 500 μg/mL SLS in vitro, lymphocyte proliferation assay of chicken peripheral blood mononuclear cells showed that the OD570 values of all experimental groups, as well as Con A-stimulated group, were significantly higher than that of the untreated control group.
After injection with 1.0, 2.0, or 4.0 mg/kg of SLS for 3 consecutive days, chickens were vaccinated with an attenuated vaccine against Newcastle disease virus (NDV), and the immunoadjuvant effects of SLS were evaluated on the basis of immune organ index, antibody response, and CD4+/CD8+ T-cell ratio.
The results confirmed that SLS could enhance NDV-specific antibody response and increase CD4+/CD8+ T-cell ratio in vivo.
Furthermore, SLS could improve NDV-specific antibody response in thiamphenicol-treated chickens.
These data indicate that SLS not only can improve humoral immune response but also reverse the immunosuppressive effect of thiamphenicol in chickens.
American Psychological Association (APA)
Cheng, DaRong& Zhu, ShanYuan& Sun, HuaiChang. 2010. The Immune Enhancement of Sodium Lauryl Sulfoacetate in Chickens. Veterinary Medicine International،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-475346
Modern Language Association (MLA)
Cheng, DaRong…[et al.]. The Immune Enhancement of Sodium Lauryl Sulfoacetate in Chickens. Veterinary Medicine International No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-475346
American Medical Association (AMA)
Cheng, DaRong& Zhu, ShanYuan& Sun, HuaiChang. The Immune Enhancement of Sodium Lauryl Sulfoacetate in Chickens. Veterinary Medicine International. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-475346
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475346