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Reconstruction of Cochlea Based on Micro-CT and Histological Images of the Human Inner Ear
Joint Authors
Fotiadis, Dimitrios I.
Böhnke, Frank
Rigas, George
Koutsouris, Dimitrios-Dionyssios
Bibas, Athanasios
Bellos, Christos
Spiridon, Ioannis F.
Iliopoulou, Dimitra
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The study of the normal function and pathology of the inner ear has unique difficulties as it is inaccessible during life and, so, conventional techniques of pathologic studies such as biopsy and surgical excision are not feasible, without further impairing function.
Mathematical modelling is therefore particularly attractive as a tool in researching the cochlea and its pathology.
The first step towards efficient mathematical modelling is the reconstruction of an accurate three dimensional (3D) model of the cochlea that will be presented in this paper.
The high quality of the histological images is being exploited in order to extract several sections of the cochlea that are not visible on the micro-CT (mCT) images (i.e., scala media, spiral ligament, and organ of Corti) as well as other important sections (i.e., basilar membrane, Reissner membrane, scala vestibule, and scala tympani).
The reconstructed model is being projected in the centerline of the coiled cochlea, extracted from mCT images, and represented in the 3D space.
The reconstruction activities are part of the SIFEM project, which will result in the delivery of an infrastructure, semantically interlinking various tools and libraries (i.e., segmentation, reconstruction, and visualization tools) with the clinical knowledge, which is represented by existing data, towards the delivery of a robust multiscale model of the inner ear.
American Psychological Association (APA)
Bellos, Christos& Rigas, George& Iliopoulou, Dimitra& Böhnke, Frank& Koutsouris, Dimitrios-Dionyssios& Fotiadis, Dimitrios I.…[et al.]. 2014. Reconstruction of Cochlea Based on Micro-CT and Histological Images of the Human Inner Ear. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-475413
Modern Language Association (MLA)
Iliopoulou, Dimitra…[et al.]. Reconstruction of Cochlea Based on Micro-CT and Histological Images of the Human Inner Ear. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-475413
American Medical Association (AMA)
Bellos, Christos& Rigas, George& Iliopoulou, Dimitra& Böhnke, Frank& Koutsouris, Dimitrios-Dionyssios& Fotiadis, Dimitrios I.…[et al.]. Reconstruction of Cochlea Based on Micro-CT and Histological Images of the Human Inner Ear. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-475413
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475413