Maternal Manganese Restriction Increases Susceptibility to High-Fat Diet-Induced Dyslipidemia and Altered Adipose Function in WNIN Male Rat Offspring
Joint Authors
Kishore, Yedla Durga
Padmavathi, Inagadapa J. Naga
Raghunath, Manchala
Venu, Lagishetty
Kumar, Kalle Anand
Ganeshan, Manisha
Rao, J. Srinivasa
Sainath, Pothaganti B.
Harishanker, Nemani
Source
Experimental Diabetes Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-11
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Growth in utero is largely a reflection of nutrient and oxygen supply to the foetus.
We studied the effects of Mn restriction per se, maternal Mn restriction, and postnatal high-fat feeding in modulating body composition, lipid metabolism and adipocyte function in Wistar/NIN (WNIN) rat offspring.
Female weanling, WNIN rats received ad libitum for 4 months, a control or Mn-restricted diet and were mated with control males.
Some restricted mothers were rehabilitated with control diet from conception (MnRC) or parturition (MnRP), and their offspring were raised on control diet.
Some restricted offspring were weaned onto control diet (MnRW), while others continued on restricted diet throughout (MnR).
A set of offspring from each group was fed high-fat diet from 9 months onwards.
Body composition, adipocytes function, and lipid metabolism were monitored in male rat offspring at regular intervals.
Maternal manganese restriction increased the susceptibility of the offspring to high-fat-induced adiposity, dyslipidaemia, and a proinflammatory state but did not affect their glycemic or insulin status.
American Psychological Association (APA)
Ganeshan, Manisha& Sainath, Pothaganti B.& Padmavathi, Inagadapa J. Naga& Venu, Lagishetty& Kishore, Yedla Durga& Kumar, Kalle Anand…[et al.]. 2011. Maternal Manganese Restriction Increases Susceptibility to High-Fat Diet-Induced Dyslipidemia and Altered Adipose Function in WNIN Male Rat Offspring. Experimental Diabetes Research،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-475477
Modern Language Association (MLA)
Ganeshan, Manisha…[et al.]. Maternal Manganese Restriction Increases Susceptibility to High-Fat Diet-Induced Dyslipidemia and Altered Adipose Function in WNIN Male Rat Offspring. Experimental Diabetes Research No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-475477
American Medical Association (AMA)
Ganeshan, Manisha& Sainath, Pothaganti B.& Padmavathi, Inagadapa J. Naga& Venu, Lagishetty& Kishore, Yedla Durga& Kumar, Kalle Anand…[et al.]. Maternal Manganese Restriction Increases Susceptibility to High-Fat Diet-Induced Dyslipidemia and Altered Adipose Function in WNIN Male Rat Offspring. Experimental Diabetes Research. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-475477
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475477