MicroRNAs in Postischemic Vascular Repair
Joint Authors
Emanueli, Costanza
Caporali, Andrea
Source
Cardiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-15
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The term angiogenesis describes the growth of endothelial sprouts from preexisting postcapillary venules.
More recently, this term has been used to generally indicate the growth and remodeling process of the primitive vascular network into a complex network during development.
In adulthood, angiogenesis is activated as a reparative process during wound healing and following ischemia, and it plays a key role in tumor growth and metastasis as well as in inflammatory diseases and diabetic retinopathy.
MicroRNAs (miRNAs) are endogenous, small, noncoding RNAs that negatively control gene expression of target mRNAs.
In this paper, we aim at describing the role of miRNAs in postischemic angiogenesis.
First, we will describe the regulation and the expression of miRNAs in endothelial cells.
Then, we will analyze the role of miRNAs in postischemic vascular repair.
Finally, we will discuss the role of circulating miRNAs as potential biomarkers in ischemic diseases.
American Psychological Association (APA)
Caporali, Andrea& Emanueli, Costanza. 2012. MicroRNAs in Postischemic Vascular Repair. Cardiology Research and Practice،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-475506
Modern Language Association (MLA)
Caporali, Andrea& Emanueli, Costanza. MicroRNAs in Postischemic Vascular Repair. Cardiology Research and Practice No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-475506
American Medical Association (AMA)
Caporali, Andrea& Emanueli, Costanza. MicroRNAs in Postischemic Vascular Repair. Cardiology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-475506
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475506