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Oxidative Stress and Air Pollution Exposure
Joint Authors
Bigagli, Elisabetta
Lodovici, Maura
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Pharmacy, Health & Medical Sciences
Medicine
Abstract EN
Air pollution is associated with increased cardiovascular and pulmonary morbidity and mortality.
The mechanisms of air pollution-induced health effects involve oxidative stress and inflammation.
As a matter of fact, particulate matter (PM), especially fine (PM2.5, PM < 2.5 μm) and ultrafine (PM0.1, PM < 0.1 μm) particles, ozone, nitrogen oxides, and transition metals, are potent oxidants or able to generate reactive oxygen species (ROS).
Oxidative stress can trigger redox-sensitive pathways that lead to different biological processes such as inflammation and cell death.
However, it does appear that the susceptibility of target organ to oxidative injury also depends upon its ability to upregulate protective scavenging systems.
As vehicular traffic is known to importantly contribute to PM exposure, its intensity and quality must be strongly relevant determinants of the qualitative characteristics of PM spread in the atmosphere.
Change in the composition of this PM is likely to modify its health impact.
American Psychological Association (APA)
Lodovici, Maura& Bigagli, Elisabetta. 2011. Oxidative Stress and Air Pollution Exposure. Journal of Toxicology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-475539
Modern Language Association (MLA)
Lodovici, Maura& Bigagli, Elisabetta. Oxidative Stress and Air Pollution Exposure. Journal of Toxicology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-475539
American Medical Association (AMA)
Lodovici, Maura& Bigagli, Elisabetta. Oxidative Stress and Air Pollution Exposure. Journal of Toxicology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-475539
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475539