The Roles of Fibroblast Growth Factors in the Testicular Development and Tumor
Joint Authors
Jiang, Xin
Zhang, Chi
Xin, Ying
Skibba, Melissa
Qu, Yaqin
Tan, Yi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Fibroblast growth factors (FGFs) are classically known as hormonal factors and recent studies have revealed that FGFs have a key role in regulating growth and development of several reproductive organs, including the testis.
The testis is mainly consisted of germ cells, Sertoli cells and Leydig cells to develop and maintain the male phenotype and reproduction.
This review summarizes the structure and fuctions of testis, the roles of FGFs on testicular development and potential involvement in testicular tumor and its regulatory mechanism.
Among 23 members of FGFs, the FGF-1, FGF-2, FGF-4, FGF-8, FGF-9, and FGF-21 were involved and describe in details.
Understanding the roles and mechanism of FGFs is the foundation to modeling testicular development and treatments in testicular disease.
Therefore, in the last part, the potential therapy with FGFs for the testis of cancer and diabetes was also discussed.
American Psychological Association (APA)
Jiang, Xin& Skibba, Melissa& Zhang, Chi& Tan, Yi& Xin, Ying& Qu, Yaqin. 2013. The Roles of Fibroblast Growth Factors in the Testicular Development and Tumor. Journal of Diabetes Research،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-475641
Modern Language Association (MLA)
Jiang, Xin…[et al.]. The Roles of Fibroblast Growth Factors in the Testicular Development and Tumor. Journal of Diabetes Research No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-475641
American Medical Association (AMA)
Jiang, Xin& Skibba, Melissa& Zhang, Chi& Tan, Yi& Xin, Ying& Qu, Yaqin. The Roles of Fibroblast Growth Factors in the Testicular Development and Tumor. Journal of Diabetes Research. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-475641
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475641