Gadoxetate Acid-Enhanced MR Imaging for HCC : A Review for Clinicians
Joint Authors
Chow, Pierce K. H.
Chanyaputhipong, Jendana
Low, Su-Chong Albert
Source
International Journal of Hepatology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-13
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Hepatocellular carcinoma (HCC) is increasingly being detected at an earlier stage, owing to the screening programs and regular imaging follow-up in high-risk populations.
Small HCCs still pose diagnostic challenges on imaging due to decreased sensitivity and increased frequency of atypical features.
Differentiating early HCC from premalignant or benign nodules is important as management differs and has implications on both the quality of life and the overall survival for the patients.
Gadoxetate acid (Gd-EOB-DTPA, Primovist®, Bayer Schering Pharma) is a relatively new, safe and well-tolerated liver-specific contrast agent for magnetic resonance (MR) imaging of the liver that has combined perfusion- and hepatocyte-specific properties, allowing for the acquisition of both dynamic and hepatobiliary phase images.
Its high biliary uptake and excretion improves lesion detection and characterization by increasing liver-to-lesion conspicuity in the added hepatobiliary phase imaging.
To date, gadoxetate acid-enhanced MRI has been mostly shown to be superior to unenhanced MRI, computed tomography, and other types of contrast agents in the detection and characterization of liver lesions.
This review article focuses on the evolving role of gadoxetate acid in the characterization of HCC, differentiating it from other mimickers of HCC.
American Psychological Association (APA)
Chanyaputhipong, Jendana& Low, Su-Chong Albert& Chow, Pierce K. H.. 2011. Gadoxetate Acid-Enhanced MR Imaging for HCC : A Review for Clinicians. International Journal of Hepatology،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-475664
Modern Language Association (MLA)
Chanyaputhipong, Jendana…[et al.]. Gadoxetate Acid-Enhanced MR Imaging for HCC : A Review for Clinicians. International Journal of Hepatology No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-475664
American Medical Association (AMA)
Chanyaputhipong, Jendana& Low, Su-Chong Albert& Chow, Pierce K. H.. Gadoxetate Acid-Enhanced MR Imaging for HCC : A Review for Clinicians. International Journal of Hepatology. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-475664
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475664