A Patient Presenting with Bilateral Lung Lesions, Pleural Effusion, and Proteinuria

Abstract EN

Diagnosis and management of a systemic vasculitis are among the most demanding challenges in clinical medicine.

A patient with a past history of cryptogenic organizing pneumonia presents with new bilateral lung lesions, unilateral pleural effusion, and significant proteinuria.

The patient tested p-ANCA and anti-MPO positive but c-ANCA negative.

A diagnosis of granulomatosis with polyangiitis GPA was reached after performing both renal and lung biopsies.

Step-by-step differential diagnosis and management are discussed.