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Primary Myeloid Sarcoma Masquerading as an Obstructing Duodenal Carcinoma
Joint Authors
Murthy, Vijayashree
Su, Mu
Chamberlain, Ronald S.
Grossman, I. Robert
Woel, Rosemonde
Narayan, Preeti
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Myeloid Sarcoma (MS), a rare extra hematopoietic carcinoma composed of blast cells, is located primarily in extramedullary sites such as skin, soft tissue, lymph nodes, and bone.
MS usually presents in the setting of coexisting acute myeloid leukemia (AML) and myeloproliferative disorders.
Gastrointestinal involvement (GI) is extremely rare from nonspecific abdominal symptoms to obstruction.
Eight cases of myeloid sarcoma involving the duodenum including the current case have been reported, overall mean age being 40 years (range 17–71) and M : F ratio 7 : 1.
The prognosis of patients with de novo MS cases has been reported to be better than those who have a coexisting leukemia.
MS is a rare extramedullary tumor, which should be considered in the differential diagnosis of a soft tissue mass involving the duodenum, especially if there is a coexisting hematological disorder.
De novo cases often progress to AML, and current therapy involves Daunorubicin- and Cytarabine-based chemotherapy.
The wide cytogenetic and molecular heterogeneity of MS implies a potential role for more targeted MS therapies, which may offer a curative strategy.
American Psychological Association (APA)
Narayan, Preeti& Murthy, Vijayashree& Su, Mu& Woel, Rosemonde& Grossman, I. Robert& Chamberlain, Ronald S.. 2012. Primary Myeloid Sarcoma Masquerading as an Obstructing Duodenal Carcinoma. Case Reports in Hematology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-475765
Modern Language Association (MLA)
Narayan, Preeti…[et al.]. Primary Myeloid Sarcoma Masquerading as an Obstructing Duodenal Carcinoma. Case Reports in Hematology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-475765
American Medical Association (AMA)
Narayan, Preeti& Murthy, Vijayashree& Su, Mu& Woel, Rosemonde& Grossman, I. Robert& Chamberlain, Ronald S.. Primary Myeloid Sarcoma Masquerading as an Obstructing Duodenal Carcinoma. Case Reports in Hematology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-475765
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475765