First- and Second-Trimester Reference Intervals for Thyroid Hormones during Pregnancy in “Rhea” Mother-Child Cohort, Crete, Greece
Joint Authors
Karakosta, Polyxeni
Alegakis, Dimitris
Kampa, Marilena
Daraki, Vasiliki
Kogevinas, Manolis
Bagkeris, Emmanouil
Castanas, Elias
Chatzi, Leda
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-04
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Estimation and interpretation of thyroid function tests in pregnant women is of utmost importance for maternal, fetal and neonatal health.
Our objective was to calculate laboratory- and geography-specific reference intervals for thyroid hormones during pregnancy in an iodine-sufficient area of the Mediterranean, Crete, Greece.
This project was performed in the context of “Rhea” mother-child cohort.
Fulfillment of extensive questionnaires and estimation of free triiodothyronine (fT3), free thyroxine (fT4), thyroid-stimulating hormone (TSH), and antithyroid antibodies were performed.
The reference population was defined using inclusion criteria regarding thyroidal, obstetric, and general medical status of women.
Reference interval for TSH was 0.05–2.53 μIU/mL for the first and 0.18–2.73 μIU/mL for the second trimester.
6,8% and 5,9% of women in the first and second trimester, respectively, had TSH higher than the upper reference limit.
These trimester-specific population-based reference ranges are essential in everyday clinical practice for the correct interpretation of thyroid hormone values and accurate classification of thyroid disorders.
American Psychological Association (APA)
Karakosta, Polyxeni& Chatzi, Leda& Bagkeris, Emmanouil& Daraki, Vasiliki& Alegakis, Dimitris& Castanas, Elias…[et al.]. 2011. First- and Second-Trimester Reference Intervals for Thyroid Hormones during Pregnancy in “Rhea” Mother-Child Cohort, Crete, Greece. Journal of Thyroid Research،Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-475806
Modern Language Association (MLA)
Karakosta, Polyxeni…[et al.]. First- and Second-Trimester Reference Intervals for Thyroid Hormones during Pregnancy in “Rhea” Mother-Child Cohort, Crete, Greece. Journal of Thyroid Research No. 2011 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-475806
American Medical Association (AMA)
Karakosta, Polyxeni& Chatzi, Leda& Bagkeris, Emmanouil& Daraki, Vasiliki& Alegakis, Dimitris& Castanas, Elias…[et al.]. First- and Second-Trimester Reference Intervals for Thyroid Hormones during Pregnancy in “Rhea” Mother-Child Cohort, Crete, Greece. Journal of Thyroid Research. 2011. Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-475806
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475806