Comprehensive Detection, Grading, and Growth Behavior Evaluation of Subthreshold and Low Intensity Photocoagulation Lesions by Optical Coherence Tomographic and Infrared Image Analysis
Joint Authors
Schlott, Kerstin
Miura, Yoko
Roider, Johann
Koinzer, Stefan
Caliebe, Amke
Saeger, Mark
Brinkmann, Ralf
Portz, Lea
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-12
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
To correlate the long-term clinical effect of photocoagulation lesions after 6 months, as measured by their retinal damage size, to exposure parameters.
We used optical coherence tomographic (OCT)-based lesion classes in order to detect and assess clinically invisible and mild lesions.
Methods.
In this prospective study, 488 photocoagulation lesions were imaged in 20 patients.
We varied irradiation diameters (100/300 µm), exposure-times (20–200 ms), and power.
Intensities were classified in OCT images after one hour, and we evaluated OCT and infrared (IR) images over six months after exposure.
Results.
For six consecutive OCT-based lesion classes, the following parameters increased with the class: ophthalmoscopic, OCT and IR visibility rate, fundus and OCT diameter, and IR area, but not irradiation power.
OCT diameters correlated with exposure-time, irradiation diameter, and OCT class.
OCT classes discriminated the largest bandwidth of OCT diameters.
Conclusion.
OCT classes represent objective and valid endpoints of photocoagulation intensity even for “subthreshold” intensities.
They are suitable to calculate the treated retinal area.
As the area is critical for treatment efficacy, OCT classes are useful to define treatment intensity, calculate necessary lesion numbers, and universally categorize lesions in clinical studies.
American Psychological Association (APA)
Koinzer, Stefan& Caliebe, Amke& Portz, Lea& Saeger, Mark& Miura, Yoko& Schlott, Kerstin…[et al.]. 2014. Comprehensive Detection, Grading, and Growth Behavior Evaluation of Subthreshold and Low Intensity Photocoagulation Lesions by Optical Coherence Tomographic and Infrared Image Analysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-475981
Modern Language Association (MLA)
Koinzer, Stefan…[et al.]. Comprehensive Detection, Grading, and Growth Behavior Evaluation of Subthreshold and Low Intensity Photocoagulation Lesions by Optical Coherence Tomographic and Infrared Image Analysis. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-475981
American Medical Association (AMA)
Koinzer, Stefan& Caliebe, Amke& Portz, Lea& Saeger, Mark& Miura, Yoko& Schlott, Kerstin…[et al.]. Comprehensive Detection, Grading, and Growth Behavior Evaluation of Subthreshold and Low Intensity Photocoagulation Lesions by Optical Coherence Tomographic and Infrared Image Analysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-475981
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-475981