Pathophysiology of the Behçet's Disease
Author
Source
Pathology Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-01
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Behçet's disease (BD) is a multisystemic disease of unknown etiology characterized by chronic relapsing oral-genital ulcers and uveitis.
Multiple systemic associations including articular, gastrointestinal, cardiopulmonary, neurologic, and vascular involvement are also observed in BD.
Although the etiopathogenesis of the disease remains unknown, increased neutrophil functions such as chemotaxis, phagocytosis, and excessive production of reactive oxygen species (ROS), including superoxide anion, which may be responsible for oxidative tissue damage seen in BD, and also immunological alterations, T lymphocyte abnormalities in both subpopulation and function have been considered to be correlated with the etiopathogenesis of BD.
There is some clinical evidence suggesting that emotional stress and hormonal alterations can influence the course and disease activity of BD.
American Psychological Association (APA)
Tursen, Umit. 2011. Pathophysiology of the Behçet's Disease. Pathology Research International،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-476022
Modern Language Association (MLA)
Tursen, Umit. Pathophysiology of the Behçet's Disease. Pathology Research International No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-476022
American Medical Association (AMA)
Tursen, Umit. Pathophysiology of the Behçet's Disease. Pathology Research International. 2011. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-476022
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476022