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Metabolic Activity Interferometer : A Powerful Tool for Testing Antibiotics
Joint Authors
Duarte, Rafael Silva
Machado, Rachel R. P.
Soares, Geraldo Luiz G.
Dutra, Rafael C.
Lesche, Bernhard
Kaplan, Maria Auxiliadora C.
Barbosa Raposo, Nádia R.
Soares de Lima Filho, Elton
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
It is demonstrated that the efficiency of antibiotics can be tested using an interferometric method.
Two antibiotics were used as models to show that an interferometric method to monitor the metabolic activity of slowly growing bacteria can be a safer method to judge antimicrobial properties of substances than conventional methods.
The susceptibility of Mycobacterium bovis to hexane extract of Pterodon emarginatus and to the well-known antibiotic rifampicin was tested with the interferometric method and with the conventional microplate method.
The microplate method revealed a potential activity of hexane extract against M.
bovis.
However, the interferometric method showed that the action of this substance is rather limited.
Also in the case of rifampicin, the interferometric method was able to detect resistant bacteria.
American Psychological Association (APA)
Machado, Rachel R. P.& Soares de Lima Filho, Elton& Dutra, Rafael C.& Barbosa Raposo, Nádia R.& Duarte, Rafael Silva& Soares, Geraldo Luiz G.…[et al.]. 2012. Metabolic Activity Interferometer : A Powerful Tool for Testing Antibiotics. Journal of Sensors،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-476094
Modern Language Association (MLA)
Machado, Rachel R. P.…[et al.]. Metabolic Activity Interferometer : A Powerful Tool for Testing Antibiotics. Journal of Sensors No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-476094
American Medical Association (AMA)
Machado, Rachel R. P.& Soares de Lima Filho, Elton& Dutra, Rafael C.& Barbosa Raposo, Nádia R.& Duarte, Rafael Silva& Soares, Geraldo Luiz G.…[et al.]. Metabolic Activity Interferometer : A Powerful Tool for Testing Antibiotics. Journal of Sensors. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-476094
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476094