Detection of Microorganisms in Granulomas That Have Been Formalin-Fixed : Review of the Literature Regarding Use of Molecular Methods
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-31
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Diseases
Abstract EN
Granuloma is an organized aggregate of immune cells that under the microscope appear as epithelioid macrophages.
A granuloma can only be diagnosed when a pathologist observes this type of inflammation under the microscope.
If a foreign body or a parasite is not observed inside the granuloma, stains for acid-fast bacilli and fungi are ordered since mycobacteria and fungi are frequently the cause of this type of inflammation.
It is calculated that 12 to 36% of granulomas do not have a specific etiology and many have wondered if with new molecular methods we could reduce this number.
This paper will summarize the frequently known causes of granulomas and will present the recent literature regarding the use of molecular techniques on tissue specimens and how these have helped in defining causative agents.
We will also briefly describe new research regarding formation and function of granulomas and how this impacts our ability to find an etiologic agent.
American Psychological Association (APA)
Guarner, Jeannette. 2012. Detection of Microorganisms in Granulomas That Have Been Formalin-Fixed : Review of the Literature Regarding Use of Molecular Methods. Scientifica،Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-476149
Modern Language Association (MLA)
Guarner, Jeannette. Detection of Microorganisms in Granulomas That Have Been Formalin-Fixed : Review of the Literature Regarding Use of Molecular Methods. Scientifica No. 2012 (2012), pp.1-16.
https://search.emarefa.net/detail/BIM-476149
American Medical Association (AMA)
Guarner, Jeannette. Detection of Microorganisms in Granulomas That Have Been Formalin-Fixed : Review of the Literature Regarding Use of Molecular Methods. Scientifica. 2012. Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-476149
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476149