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Tea Polyphenols Regulate Key Mediators on Inflammatory Cardiovascular Diseases
Joint Authors
Morishita, Ryuichi
Isobe, Mitsuaki
Suzuki, Jun-ichi
Nagai, Ryozo
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-07-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Tea polyphenols known as catechins are key components with many biological functions, including anti-inflammatory, antioxidative, and anticarcinogenic effects.
These effects are induced by the suppression of several inflammatory factors including nuclear factor-kappa B (NF-κB).
While these characteristics of catechins have been well documented, actions of catechins as mediators on inflammation-related cardiovascular diseases have not yet been well investigated.
In this article, we reviewed recent papers to reveal the anti-inflammatory effects of catechins in cardiovascular diseases.
In our laboratory, we performed oral administration of catechins into murine and rat models of cardiac transplantation, myocarditis, myocardial ischemia, and atherosclerosis to reveal the effects of catechins on the inflammation-induced ventricular and arterial remodeling.
From our results, catechins are potent agents for the treatment and prevention of inflammation-related cardiovascular diseases because they are critically involved in the suppression of proinflammatory signaling pathways.
American Psychological Association (APA)
Suzuki, Jun-ichi& Isobe, Mitsuaki& Morishita, Ryuichi& Nagai, Ryozo. 2009. Tea Polyphenols Regulate Key Mediators on Inflammatory Cardiovascular Diseases. Mediators of Inflammation،Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-476180
Modern Language Association (MLA)
Suzuki, Jun-ichi…[et al.]. Tea Polyphenols Regulate Key Mediators on Inflammatory Cardiovascular Diseases. Mediators of Inflammation No. 2009 (2009), pp.1-5.
https://search.emarefa.net/detail/BIM-476180
American Medical Association (AMA)
Suzuki, Jun-ichi& Isobe, Mitsuaki& Morishita, Ryuichi& Nagai, Ryozo. Tea Polyphenols Regulate Key Mediators on Inflammatory Cardiovascular Diseases. Mediators of Inflammation. 2009. Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-476180
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476180