In Vitro Antibacterial, Antioxidant, and Cytotoxic Activities of Parthenium hysterophorus and Characterization of Extracts by LC-MS Analysis
Joint Authors
Pandey, Sanjay
Kumar, Shashank
Pandey, Abhay K.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-07
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Present work reports the biological activities of P.
hysterophorus leaf, stem, flower, and root.
Dried samples were sequentially extracted with many solvents.
Hexane (HX), benzene (BZ), and chloroform (CH) extracts of leaf showed considerable antibacterial activity against Streptococcus mutans (MTCC 497), Proteus vulgaris (MTCC 7299), and Salmonella typhi (MTCC 3917).
Flower extracts exhibited presence of higher amount of flavonoids (13.9–59.6 μgQE/mg) followed by leaf, stem, and root.
Stem (HX, BZ, and CH), leaf ethanol (ET), and root (HX, BZ, and CH) fractions showed noticeable antioxidant capacity in phosphomolybdate assay.
Most of the extracts demonstrated beta carotene bleaching inhibition capability.
BZ, ethyl acetate (EA), and ET fractions of leaves, stem aqueous (AQ), and flower EA extracts showed membrane protective activities (40–55%).
Middle fractions of the plant parts displayed moderate antihemolytic potential.
Most of the flower extracts exhibited cytotoxic activity (80–100%) against lung and colon cancer cell lines.
Root (HX and ET) and leaf ET extracts showed considerable inhibition (90–99%) of colon and ovary cancer cell lines.
The LC-MS scan demonstrated presence of different compounds showing 3–20 min retention time.
The study revealed considerable antibacterial, antioxidant, lipo-protective, antihemolytic, and anticancer potential in all parts of P.
hysterophorus.
American Psychological Association (APA)
Kumar, Shashank& Pandey, Sanjay& Pandey, Abhay K.. 2014. In Vitro Antibacterial, Antioxidant, and Cytotoxic Activities of Parthenium hysterophorus and Characterization of Extracts by LC-MS Analysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-476198
Modern Language Association (MLA)
Kumar, Shashank…[et al.]. In Vitro Antibacterial, Antioxidant, and Cytotoxic Activities of Parthenium hysterophorus and Characterization of Extracts by LC-MS Analysis. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-476198
American Medical Association (AMA)
Kumar, Shashank& Pandey, Sanjay& Pandey, Abhay K.. In Vitro Antibacterial, Antioxidant, and Cytotoxic Activities of Parthenium hysterophorus and Characterization of Extracts by LC-MS Analysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-476198
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476198