Warthin Tumor-Like Papillary Thyroid Carcinoma with a Minor Dedifferentiated Component : Report of a Case with Clinicopathologic Considerations
Joint Authors
Caltabiano, Rosario
Vecchio, Giada Maria
Amico, Paolo
Lanzafame, Salvatore
Magro, Gaetano
Greco, Paolo
Li Destri, Giovanni
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Warthin tumor-like papillary thyroid carcinoma is an uncommon variant of papillary thyroid carcinoma.
We report a rare case of Warthin tumor-like variant of papillary thyroid carcinoma with a dedifferentiated component consisting of a solid tumor area composed of neoplastic cells with a spindle to tall cell morphology associated with marked nuclear pleomorphism, atypical mitoses, and foci of necrosis.
Although our patient presented with a locally aggressive disease (T3 N1b Mo), she is disease-free without radioiodine therapy after a 23-month follow-up period.
We emphasize that Warthin tumor-like papillary thyroid carcinoma, like other morphological variants of papillary carcinoma, may occasionally undergo dedifferentiation.
As this component may be only focally detectable, we suggest an extensive sampling of all large-sized (>3 cm) papillary thyroid carcinoma.
Recognition of any dedifferentiated component in a Warthin tumor-like papillary thyroid carcinoma should be reported, including its percentage, because it may reflect a more aggressive clinical course.
American Psychological Association (APA)
Amico, Paolo& Lanzafame, Salvatore& Li Destri, Giovanni& Greco, Paolo& Caltabiano, Rosario& Vecchio, Giada Maria…[et al.]. 2010. Warthin Tumor-Like Papillary Thyroid Carcinoma with a Minor Dedifferentiated Component : Report of a Case with Clinicopathologic Considerations. Case Reports in Medicine،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-476213
Modern Language Association (MLA)
Amico, Paolo…[et al.]. Warthin Tumor-Like Papillary Thyroid Carcinoma with a Minor Dedifferentiated Component : Report of a Case with Clinicopathologic Considerations. Case Reports in Medicine No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-476213
American Medical Association (AMA)
Amico, Paolo& Lanzafame, Salvatore& Li Destri, Giovanni& Greco, Paolo& Caltabiano, Rosario& Vecchio, Giada Maria…[et al.]. Warthin Tumor-Like Papillary Thyroid Carcinoma with a Minor Dedifferentiated Component : Report of a Case with Clinicopathologic Considerations. Case Reports in Medicine. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-476213
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476213