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Peritoneal Adipocytes and Their Role in Inflammation during Peritoneal Dialysis
Joint Authors
Leung, Joseph C. K.
Lai, Kar Neng
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-05
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Adipose tissue is a major site of chronic inflammation associated with peritoneal dialysis (PD) frequently complicating peritonitis.
Adiposity-associated inflammation plays a significant contributory role in the development of chronic inflammation in patients undergoing maintenance PD.
However, the molecular and cellular mechanisms of this link remain uncertain.
Adipose tissue synthesizes different adipokines and cytokines that orchestrate and regulate inflammation, insulin action, and glucose metabolism locally and systemically.
In return, inflammation retards adipocyte differentiation and further exacerbates adipose dysfunction and inflammation.
An understanding of the inflammatory roles played by adipose tissue during PD and the healing mechanism of injured mesothelium will help to devise new therapeutic approach to slow the progression of peritoneal damage during peritoneal dialysis.
This article reviews the roles of peritoneal adipose tissue in chronic peritoneal inflammation under PD and in serosal repair during PD.
American Psychological Association (APA)
Lai, Kar Neng& Leung, Joseph C. K.. 2010. Peritoneal Adipocytes and Their Role in Inflammation during Peritoneal Dialysis. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-476228
Modern Language Association (MLA)
Lai, Kar Neng& Leung, Joseph C. K.. Peritoneal Adipocytes and Their Role in Inflammation during Peritoneal Dialysis. Mediators of Inflammation No. 2010 (2010), pp.1-10.
https://search.emarefa.net/detail/BIM-476228
American Medical Association (AMA)
Lai, Kar Neng& Leung, Joseph C. K.. Peritoneal Adipocytes and Their Role in Inflammation during Peritoneal Dialysis. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-476228
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476228