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Animal Models of Cardiovascular Diseases
Joint Authors
Mallavia, Beñat
Arduán, Alberto Ortiz
Blanco-Colio, Luis Miguel
Gomez-Guerrero, Carmen
Tarin, Carlos
Jose Luis, Martin-Ventura
Lavin, Begoña
Zaragoza, Carlos
Mas, Sebastian
Egido, Jesus
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-16
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Cardiovascular diseases are the first leading cause of death and morbidity in developed countries.
The use of animal models have contributed to increase our knowledge, providing new approaches focused to improve the diagnostic and the treatment of these pathologies.
Several models have been developed to address cardiovascular complications, including atherothrombotic and cardiac diseases, and the same pathology have been successfully recreated in different species, including small and big animal models of disease.
However, genetic and environmental factors play a significant role in cardiovascular pathophysiology, making difficult to match a particular disease, with a single experimental model.
Therefore, no exclusive method perfectly recreates the human complication, and depending on the model, additional considerations of cost, infrastructure, and the requirement for specialized personnel, should also have in mind.
Considering all these facts, and depending on the budgets available, models should be selected that best reproduce the disease being investigated.
Here we will describe models of atherothrombotic diseases, including expanding and occlusive animal models, as well as models of heart failure.
Given the wide range of models available, today it is possible to devise the best strategy, which may help us to find more efficient and reliable solutions against human cardiovascular diseases.
American Psychological Association (APA)
Zaragoza, Carlos& Gomez-Guerrero, Carmen& Jose Luis, Martin-Ventura& Blanco-Colio, Luis Miguel& Lavin, Begoña& Mallavia, Beñat…[et al.]. 2011. Animal Models of Cardiovascular Diseases. Journal of Biomedicine and Biotechnology،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-476432
Modern Language Association (MLA)
Zaragoza, Carlos…[et al.]. Animal Models of Cardiovascular Diseases. Journal of Biomedicine and Biotechnology No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-476432
American Medical Association (AMA)
Zaragoza, Carlos& Gomez-Guerrero, Carmen& Jose Luis, Martin-Ventura& Blanco-Colio, Luis Miguel& Lavin, Begoña& Mallavia, Beñat…[et al.]. Animal Models of Cardiovascular Diseases. Journal of Biomedicine and Biotechnology. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-476432
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476432