Phenytoin-Induced Gingival Overgrowth : A Review of the Molecular, Immune, and Inflammatory Features
Joint Authors
Costa, José Eustáquio
Queiroz-Junior, Celso Martins
Silva, Tarcilia Aparecida
Corrêa, Jôice Dias
Teixeira, Antônio Lúcio
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Gingival overgrowth (GO) is a side effect associated with some distinct classes of drugs, such as anticonvulsants, immunosuppressant, and calcium channel blockers.
GO is characterized by the accumulation of extracellular matrix in gingival connective tissues, particularly collagenous components, with varying degrees of inflammation.
One of the main drugs associated with GO is the antiepileptic phenytoin, which affects gingival tissues by altering extracellular matrix metabolism.
Nevertheless, the pathogenesis of such drug-induced GO remains fulfilled by some contradictory findings.
This paper aims to present the most relevant studies regarding the molecular, immune, and inflammatory aspects of phenytoin-induced gingival overgrowth.
American Psychological Association (APA)
Corrêa, Jôice Dias& Queiroz-Junior, Celso Martins& Costa, José Eustáquio& Teixeira, Antônio Lúcio& Silva, Tarcilia Aparecida. 2011. Phenytoin-Induced Gingival Overgrowth : A Review of the Molecular, Immune, and Inflammatory Features. ISRN Dentistry،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-476433
Modern Language Association (MLA)
Corrêa, Jôice Dias…[et al.]. Phenytoin-Induced Gingival Overgrowth : A Review of the Molecular, Immune, and Inflammatory Features. ISRN Dentistry No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-476433
American Medical Association (AMA)
Corrêa, Jôice Dias& Queiroz-Junior, Celso Martins& Costa, José Eustáquio& Teixeira, Antônio Lúcio& Silva, Tarcilia Aparecida. Phenytoin-Induced Gingival Overgrowth : A Review of the Molecular, Immune, and Inflammatory Features. ISRN Dentistry. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-476433
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476433