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Estrogens and Spermiogenesis : New Insights from Type 1 Cannabinoid Receptor Knockout Mice
Joint Authors
Cobellis, Gilda
Chioccarelli, Teresa
Pierantoni, Riccardo
Fasano, Silvia
Cacciola, Giovanna
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Spermatogenesis is a complex mechanism which allows the production of male gametes; it consists of mitotic, meiotic, and differentiation phases.
Spermiogenesis is the terminal differentiation process during which haploid round spermatids undergo several biochemical and morphological changes, including extensive remodelling of chromatin and nuclear shape.
Spermiogenesis is under control of endocrine, paracrine, and autocrine factors, like gonadotropins and testosterone.
More recently, emerging pieces of evidence are suggesting that, among these factors, estrogens may have a role.
To date, this is a matter of debate and concern because of the agonistic and antagonistic estrogenic effects that environmental chemicals may have on animal and human with damaging outcome on fertility.
In this review, we summarize data which fuel this debate, with a particular attention to our recent results, obtained using type 1 cannabinoid receptor knockout male mice as animal model.
American Psychological Association (APA)
Cacciola, Giovanna& Chioccarelli, Teresa& Fasano, Silvia& Pierantoni, Riccardo& Cobellis, Gilda. 2013. Estrogens and Spermiogenesis : New Insights from Type 1 Cannabinoid Receptor Knockout Mice. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-476564
Modern Language Association (MLA)
Cacciola, Giovanna…[et al.]. Estrogens and Spermiogenesis : New Insights from Type 1 Cannabinoid Receptor Knockout Mice. International Journal of Endocrinology No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-476564
American Medical Association (AMA)
Cacciola, Giovanna& Chioccarelli, Teresa& Fasano, Silvia& Pierantoni, Riccardo& Cobellis, Gilda. Estrogens and Spermiogenesis : New Insights from Type 1 Cannabinoid Receptor Knockout Mice. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-476564
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476564