Cellular Reprogramming toward the Erythroid Lineage
Joint Authors
Crossley, Merlin
Funnell, Alister P. W.
Norton, Laura J.
Pearson, Richard C. M.
Source
International Journal of Cell Biology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Haemoglobinopathies such as thalassaemia and sickle cell disease present a major health burden.
Currently, the main forms of treatment for these diseases are packed red blood cell transfusions and the administration of drugs which act to nonspecifically reactivate the production of foetal haemoglobin.
These treatments are ongoing throughout the life of the patient and are associated with a number of risks, such as limitations in available blood for transfusion, infections, iron overload, immune rejection, and side effects associated with the drug treatments.
The field of cellular reprogramming has advanced significantly in the last few years and has recently culminated in the successful production of erythrocytes in culture.
This paper will discuss cellular reprogramming and its potential relevance to the treatment of haemoglobinopathies.
American Psychological Association (APA)
Norton, Laura J.& Funnell, Alister P. W.& Pearson, Richard C. M.& Crossley, Merlin. 2011. Cellular Reprogramming toward the Erythroid Lineage. International Journal of Cell Biology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-476579
Modern Language Association (MLA)
Norton, Laura J.…[et al.]. Cellular Reprogramming toward the Erythroid Lineage. International Journal of Cell Biology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-476579
American Medical Association (AMA)
Norton, Laura J.& Funnell, Alister P. W.& Pearson, Richard C. M.& Crossley, Merlin. Cellular Reprogramming toward the Erythroid Lineage. International Journal of Cell Biology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-476579
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476579