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Cannabinoids for the Treatment of Schizophrenia? A Balanced Neurochemical Framework for Both Adverse and Therapeutic Effects of Cannabis Use
Joint Authors
Perdices, Michael
Henderson, Antony F.
Coulston, Carissa M.
Malhi, Gin S.
Source
Schizophrenia Research and Treatment
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-07-27
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Recent studies have found that cannabinoids may improve neuropsychological performance, ameliorate negative symptoms, and have antipsychotic properties for a subgroup of the schizophrenia population.
These findings are in contrast to the longstanding history of adverse consequences of cannabis use, predominantly on the positive symptoms, and a balanced neurochemical basis for these opposing views is lacking.
This paper details a review of the neurobiological substrates of schizophrenia and the neurochemical effects of cannabis use in the normal population, in both cortical (in particular prefrontal) and subcortical brain regions.
The aim of this paper is to provide a holistic neurochemical framework in which to understand how cannabinoids may impair, or indeed, serve to ameliorate the positive and negative symptoms as well as cognitive impairment.
Directions in which future research can proceed to resolve the discrepancies are briefly discussed.
American Psychological Association (APA)
Coulston, Carissa M.& Perdices, Michael& Henderson, Antony F.& Malhi, Gin S.. 2010. Cannabinoids for the Treatment of Schizophrenia? A Balanced Neurochemical Framework for Both Adverse and Therapeutic Effects of Cannabis Use. Schizophrenia Research and Treatment،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-476609
Modern Language Association (MLA)
Coulston, Carissa M.…[et al.]. Cannabinoids for the Treatment of Schizophrenia? A Balanced Neurochemical Framework for Both Adverse and Therapeutic Effects of Cannabis Use. Schizophrenia Research and Treatment No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-476609
American Medical Association (AMA)
Coulston, Carissa M.& Perdices, Michael& Henderson, Antony F.& Malhi, Gin S.. Cannabinoids for the Treatment of Schizophrenia? A Balanced Neurochemical Framework for Both Adverse and Therapeutic Effects of Cannabis Use. Schizophrenia Research and Treatment. 2010. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-476609
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476609