Assessment and Molecular Actions of Endocrine-Disrupting Chemicals That Interfere with Estrogen Receptor Pathways
Joint Authors
Habauzit, Denis
Pakdel, Farzad
Kerdivel, Gwenneg
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-02
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
In all vertebrate species, estrogens play a crucial role in the development, growth, and function of reproductive and nonreproductive tissues.
A large number of natural or synthetic chemicals present in the environment and diet can interfere with estrogen signaling; these chemicals are called endocrine disrupting chemicals (EDCs) or xenoestrogens.
Some of these compounds have been shown to induce adverse effects on human and animal health, and some compounds are suspected to contribute to diverse disease development.
Because xenoestrogens have varying sources and structures and could act in additive or synergistic effects when combined, they have multiple mechanisms of action.
Consequently, an important panel of in vivo and in vitro bioassays and chemical analytical tools was used to screen, evaluate, and characterize the potential impacts of these compounds on humans and animals.
In this paper, we discuss different molecular actions of some of the major xenoestrogens found in food or the environment, and we summarize the current models used to evaluate environmental estrogens.
American Psychological Association (APA)
Kerdivel, Gwenneg& Habauzit, Denis& Pakdel, Farzad. 2013. Assessment and Molecular Actions of Endocrine-Disrupting Chemicals That Interfere with Estrogen Receptor Pathways. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-476627
Modern Language Association (MLA)
Kerdivel, Gwenneg…[et al.]. Assessment and Molecular Actions of Endocrine-Disrupting Chemicals That Interfere with Estrogen Receptor Pathways. International Journal of Endocrinology No. 2013 (2013), pp.1-14.
https://search.emarefa.net/detail/BIM-476627
American Medical Association (AMA)
Kerdivel, Gwenneg& Habauzit, Denis& Pakdel, Farzad. Assessment and Molecular Actions of Endocrine-Disrupting Chemicals That Interfere with Estrogen Receptor Pathways. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-476627
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476627