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Role of Barium Esophagography in Patients with Locally Advanced Esophageal Cancer : Evaluation of Response to Neoadjuvant Chemoradiotherapy
Joint Authors
Shioyama, Yoshiyuki
Honda, Hiroshi
Morita, Masaru
Hiraka, Kiyohisa
Komori, Masahiro
Tsurumaru, Daisuke
Source
Radiology Research and Practice
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
This retrospective study examined the usefulness of barium esophagography, focusing on the luminal stenosis, in the response evaluation of neoadjuvant chemoradiotherapy (NACRT) in patients with esophageal cancer.
Materials and Methods.
Thirty-four patients with primary advanced esophageal cancer (≥T2) who were treated with NACRT before surgical resection were analyzed.
All patients underwent barium esophagography before and after NACRT.
The tumor length, volume, and percent esophageal stenosis (PES) before and after NACRT were measured.
These values and their changes were compared between histopathologic responders (n=22) and nonresponders (n=12).
Results.
Posttreatment tumor length and PES in responders (4.5 cm ± 1.1 and 33.0% ± 18.5) were significantly smaller than those in nonresponders (5.8 cm ± 1.9 and 48.0% ± 12.9) (P=0.018).
Regarding posttherapeutic changes, the decrease in PES in responders (31.5% ± 13.9) was significantly greater than that in nonresponders (14.4% ± 10.7) (P<0.001).
The best decrease in PES cutoff with which to differentiate between responders and nonresponders was 18.8%, which yielded a sensitivity of 91% and a specificity of 75%.
Conclusions.
Decrease in PES is a good parameter to differentiate responders from nonresponders for NACRT.
Barium esophagography is useful in response evaluation to NACRT in patients with locally advanced esophageal cancer.
American Psychological Association (APA)
Tsurumaru, Daisuke& Hiraka, Kiyohisa& Komori, Masahiro& Shioyama, Yoshiyuki& Morita, Masaru& Honda, Hiroshi. 2013. Role of Barium Esophagography in Patients with Locally Advanced Esophageal Cancer : Evaluation of Response to Neoadjuvant Chemoradiotherapy. Radiology Research and Practice،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-476712
Modern Language Association (MLA)
Tsurumaru, Daisuke…[et al.]. Role of Barium Esophagography in Patients with Locally Advanced Esophageal Cancer : Evaluation of Response to Neoadjuvant Chemoradiotherapy. Radiology Research and Practice No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-476712
American Medical Association (AMA)
Tsurumaru, Daisuke& Hiraka, Kiyohisa& Komori, Masahiro& Shioyama, Yoshiyuki& Morita, Masaru& Honda, Hiroshi. Role of Barium Esophagography in Patients with Locally Advanced Esophageal Cancer : Evaluation of Response to Neoadjuvant Chemoradiotherapy. Radiology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-476712
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476712