Computational Vaccinology : An Important Strategy to Discover New Potential S. mansoni Vaccine Candidates
Joint Authors
Assis, Natan R. G.
Martins, Vicente P.
Morais, Suellen B.
Azevedo, Vasco
Figueiredo, Bárbara C. P.
Pinheiro, Carina S.
Oliveira, Sergio Costa
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The flatworm Schistosoma mansoni is a blood fluke parasite that causes schistosomiasis, a debilitating disease that occurs throughout the developing world.
Current schistosomiasis control strategies are mainly based on chemotherapy, but many researchers believe that the best long-term strategy to control schistosomiasis is through immunization with an antischistosomiasis vaccine combined with drug treatment.
Several papers on Schistosoma mansoni vaccine and drug development have been published in the past few years, representing an important field of study.
The advent of technologies that allow large-scale studies of genes and proteins had a remarkable impact on the screening of new and potential vaccine candidates in schistosomiasis.
In this postgenomic scenario, bioinformatic technologies have emerged as important tools to mine transcriptomic, genomic, and proteomic databases.
These new perspectives are leading to a new round of rational vaccine development.
Herein, we discuss different strategies to identify potential S.
mansoni vaccine candidates using computational vaccinology.
American Psychological Association (APA)
Pinheiro, Carina S.& Martins, Vicente P.& Assis, Natan R. G.& Figueiredo, Bárbara C. P.& Morais, Suellen B.& Azevedo, Vasco…[et al.]. 2011. Computational Vaccinology : An Important Strategy to Discover New Potential S. mansoni Vaccine Candidates. Journal of Biomedicine and Biotechnology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-476757
Modern Language Association (MLA)
Pinheiro, Carina S.…[et al.]. Computational Vaccinology : An Important Strategy to Discover New Potential S. mansoni Vaccine Candidates. Journal of Biomedicine and Biotechnology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-476757
American Medical Association (AMA)
Pinheiro, Carina S.& Martins, Vicente P.& Assis, Natan R. G.& Figueiredo, Bárbara C. P.& Morais, Suellen B.& Azevedo, Vasco…[et al.]. Computational Vaccinology : An Important Strategy to Discover New Potential S. mansoni Vaccine Candidates. Journal of Biomedicine and Biotechnology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-476757
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476757