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The Efficacy and Safety of Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis for Treatment of Pain in Patients with Pancreatic Cancer
Joint Authors
Boer, Klaudiusz
Wiechowska-Kozłowska, Anna
Milkiewicz, Piotr
Wójcicki, Maciej
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Celiac plexus neurolysis is used in pain management of patients with advanced and unresectable pancreatic cancer.
We retrospectively analyzed efficacy and safety of endoscopic ultrasound- (EUS-) guided celiac plexus neurolysis in patients treated in our unit.
Methods.
Twenty nine subjects with unresectable pancreatic cancer and severe pain despite pharmacological treatment underwent EUS-guided celiac plexus neurolysis with 98% ethanol.
Patients scored their pain according to a 0–10 point scale and were interviewed 1-2 weeks and 2-3 months after the procedure.
Results.
Twenty five (86%) patients reported improvement in their pain at 1-2 weeks following the procedure.
Of these, 7 (24%) reported substantial improvement (decrease in pain by more than 50%) and 4 (14%) complete disappearance of pain.
Pain relief was still present in 76% of patients after 2-3 months.
Treatment-related side effects included hypotonia in 1 patient, severe pain immediately postprocedure in 2 patients, and short episodes of diarrhea in 3 patients.
Conclusion.
Endoscopic ultrasound- (EUS-) guided celiac plexus neurolysis is a safe and effective treatment of severe pain from advanced pancreatic cancer.
American Psychological Association (APA)
Wiechowska-Kozłowska, Anna& Boer, Klaudiusz& Wójcicki, Maciej& Milkiewicz, Piotr. 2012. The Efficacy and Safety of Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis for Treatment of Pain in Patients with Pancreatic Cancer. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-476759
Modern Language Association (MLA)
Wiechowska-Kozłowska, Anna…[et al.]. The Efficacy and Safety of Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis for Treatment of Pain in Patients with Pancreatic Cancer. Gastroenterology Research and Practice No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-476759
American Medical Association (AMA)
Wiechowska-Kozłowska, Anna& Boer, Klaudiusz& Wójcicki, Maciej& Milkiewicz, Piotr. The Efficacy and Safety of Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis for Treatment of Pain in Patients with Pancreatic Cancer. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-476759
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476759