Computational Fluid Dynamics Analysis of the Effect of Plaques in the Left Coronary Artery
Joint Authors
Sun, Zhonghua
Chaichana, Thanapong
Jewkes, James
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-12
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
This study was to investigate the hemodynamic effect of simulated plaques in left coronary artery models, which were generated from a sample patient’s data.
Plaques were simulated and placed at the left main stem and the left anterior descending (LAD) to produce at least 60% coronary stenosis.
Computational fluid dynamics analysis was performed to simulate realistic physiological conditions that reflect the in vivo cardiac hemodynamics, and comparison of wall shear stress (WSS) between Newtonian and non-Newtonian fluid models was performed.
The pressure gradient (PSG) and flow velocities in the left coronary artery were measured and compared in the left coronary models with and without presence of plaques during cardiac cycle.
Our results showed that the highest PSG was observed in stenotic regions caused by the plaques.
Low flow velocity areas were found at postplaque locations in the left circumflex, LAD, and bifurcation.
WSS at the stenotic locations was similar between the non-Newtonian and Newtonian models although some more details were observed with non-Newtonian model.
There is a direct correlation between coronary plaques and subsequent hemodynamic changes, based on the simulation of plaques in the realistic coronary models.
American Psychological Association (APA)
Chaichana, Thanapong& Sun, Zhonghua& Jewkes, James. 2012. Computational Fluid Dynamics Analysis of the Effect of Plaques in the Left Coronary Artery. Computational and Mathematical Methods in Medicine،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-476873
Modern Language Association (MLA)
Chaichana, Thanapong…[et al.]. Computational Fluid Dynamics Analysis of the Effect of Plaques in the Left Coronary Artery. Computational and Mathematical Methods in Medicine No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-476873
American Medical Association (AMA)
Chaichana, Thanapong& Sun, Zhonghua& Jewkes, James. Computational Fluid Dynamics Analysis of the Effect of Plaques in the Left Coronary Artery. Computational and Mathematical Methods in Medicine. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-476873
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476873