Effects of Three Types of Japanese Honey on Full-Thickness Wound in Mice
Joint Authors
Kitayama, Yukie
Hiratoko, Yukiho
Mukai, Kanae
Nishino, Kasumi
Yokokawa, Yoshika
Tsuruhara, Yusuke
Nakatani, Toshio
Hayashi, Natsumi
Iuchi, Terumi
Kinoshita, Ayaka
Kon, Yuka
Fuwano, Sono
Nakajima, Yukari
Murakado, Naoko
Okuwa, Mayumi
Miyahara, Megumi
Nakano, Yuki
Mochizuki, Tsuyoshi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-20
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Although many previous studies reported that honey promotes wound healing, no study has examined the effects of Japanese honey.
The aim of this study was to investigate the effects of three types of Japanese honey, Acacia, Buckwheat flour, and Chinese milk vetch honey, on wound healing in comparison with hydrocolloid dressing.
Circular full-thickness skin wounds were produced on male mice.
Japanese honey or hydrocolloid dressing was applied daily to the mice for 14 days.
The ratio of wound area for the hydrocolloid dressing group increased initially in the inflammatory and early proliferative phases and then decreased rapidly to heal with scarring.
However, the ratios of wound area for the Japanese honey groups decreased in the inflammatory phase, increased in the proliferative phase, and decreased in the proliferative phase, and some wounds were not completely covered with new epithelium.
These findings indicate that using Japanese honey alone has limited benefit, but since it reduces wound size in the inflammatory phase, it is possible to apply a combined treatment in which Japanese honey is applied only in the inflammatory phase, followed by hydrocolloid dressing from the proliferative phase, which would effectively contract the wound.
American Psychological Association (APA)
Nakajima, Yukari& Nakano, Yuki& Fuwano, Sono& Hayashi, Natsumi& Hiratoko, Yukiho& Kinoshita, Ayaka…[et al.]. 2013. Effects of Three Types of Japanese Honey on Full-Thickness Wound in Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-476879
Modern Language Association (MLA)
Nakajima, Yukari…[et al.]. Effects of Three Types of Japanese Honey on Full-Thickness Wound in Mice. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-476879
American Medical Association (AMA)
Nakajima, Yukari& Nakano, Yuki& Fuwano, Sono& Hayashi, Natsumi& Hiratoko, Yukiho& Kinoshita, Ayaka…[et al.]. Effects of Three Types of Japanese Honey on Full-Thickness Wound in Mice. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-476879
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-476879