The Use of NeuroAiD (MLC601) in Postischemic Stroke Patients
Joint Authors
Baroque II, Alejandro C.
Navarro, Jose C.
Molina, Mark C.
Lokin, Johnny K.
Source
Rehabilitation Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Aim.
We aimed to assess the efficacy of MLC601 on functional recovery in patients given MLC601 after an ischemic stroke.
Methods.
This is a retrospective cohort study comparing poststroke patients given open-label MLC601 (n=30; 9 female) for three months and matching patients who did not receive MLC601 from our Stroke Data Bank.
Outcome assessed was modified Rankin Scale (mRS) at three months and analyzed according to: (1) achieving a score of 0-2, (2) achieving a score of 0-1, and (3) mean change in scores from baseline.
Results.
At three months, 21 patients on MLC601 became independent as compared to 17 patients not on MLC601 (OR 1.79; 95% CI 0.62–5.2; P=0.29).
There were twice as many patients (n=16) on MLC601 who attained mRS scores similar to their prestroke state than in the non-MLC601 group (n=8) (OR 3.14; 95% CI 1.1–9.27; P=0.038).
Mean improvement in mRS from baseline was better in the MLC601 group than in the non-MLC601 group (−1.7 versus −0.9; mean difference −0.73; 95% CI −1.09 to −0.38; P<0.001).
Conclusion.
MLC601 improves functional recovery at 3 months postischemic stroke.
An ongoing large randomized control trial of MLC601 will help validate these results.
American Psychological Association (APA)
Navarro, Jose C.& Molina, Mark C.& Baroque II, Alejandro C.& Lokin, Johnny K.. 2012. The Use of NeuroAiD (MLC601) in Postischemic Stroke Patients. Rehabilitation Research and Practice،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-477053
Modern Language Association (MLA)
Navarro, Jose C.…[et al.]. The Use of NeuroAiD (MLC601) in Postischemic Stroke Patients. Rehabilitation Research and Practice No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-477053
American Medical Association (AMA)
Navarro, Jose C.& Molina, Mark C.& Baroque II, Alejandro C.& Lokin, Johnny K.. The Use of NeuroAiD (MLC601) in Postischemic Stroke Patients. Rehabilitation Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-477053
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477053