Hyperammonemia : A Report of Maternal Biliary Cirrhosis and Neonatal Outcome
Joint Authors
Nelson, David B.
Shivvers, Stephan A.
Hussamy, Deana J.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-12
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Although uncommon during pregnancy, cirrhosis results in multiple medical complications impacting both mother and fetus.
Previous reports suggest liver dysfunction in pregnancy causes accumulation of neurotoxins within the maternal compartment that increases neonatal morbidity through placental transfer.
We present a case of a 36-year-old G2P1 female with history of biliary cirrhosis presenting at 32-weeks' gestation with hepatic congestion progressing to hepatic encephalopathy prompting delivery.
Umbilical cord sampling and postnatal infant testing demonstrated elevated ammonia levels which resolved by 12 hours of life without intervention.
At discharge, the infant did not demonstrate evidence of neurologic deficit.
We conclude that acute maternal hepatic encephalopathy and hyperammonemia due to chronic liver disease do not portend adverse neonatal outcomes, notably encephalopathy.
American Psychological Association (APA)
Hussamy, Deana J.& Nelson, David B.& Shivvers, Stephan A.. 2013. Hyperammonemia : A Report of Maternal Biliary Cirrhosis and Neonatal Outcome. Case Reports in Critical Care،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-477117
Modern Language Association (MLA)
Hussamy, Deana J.…[et al.]. Hyperammonemia : A Report of Maternal Biliary Cirrhosis and Neonatal Outcome. Case Reports in Critical Care No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-477117
American Medical Association (AMA)
Hussamy, Deana J.& Nelson, David B.& Shivvers, Stephan A.. Hyperammonemia : A Report of Maternal Biliary Cirrhosis and Neonatal Outcome. Case Reports in Critical Care. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-477117
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477117