Preventive Effect of Zea mays L. (Purple Waxy Corn) on Experimental Diabetic Cataract
Joint Authors
Thiraphatthanavong, Paphaphat
Wattanathorn, Jintanaporn
Lertrat, Kamol
Tong-Un, Terdthai
Wannanon, Panakaporn
Muchimapura, Supaporn
Thukham-mee, Wipawee
Suriharn, Bhalang
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Recently, substances possessing antioxidant can prevent cataractogenesis of diabetic cataract.
Therefore, this study was carried out to determine the anticataract effect of Zea mays L.
(purple waxy corn), a flavonoids rich plant, in experimental diabetic cataract.
Enucleated rat lenses were incubated in artificial aqueous humor containing 55 mM glucose with various concentrations of Zea mays L.
(purple waxy corn) ranging between 2, 10, and 50 mg/mL at room temperature for 72 h.
At the end of the incubation period, the evaluation of lens opacification, MDA level, and the activities of SOD, CAT, GPx, and AR in lens were performed.
The results showed that both medium and high doses of extract decreased lens opacity together with the decreased MDA level.
In addition, medium dose of extract increased GPx activity while the high dose decreased AR activity.
No other significant changes were observed.
The purple waxy corn seeds extract is the potential candidate to protect against diabetic cataract.
The mechanism of action may occur via the decreased oxidative stress and the suppression of AR.
However, further research in vivo is still essential.
American Psychological Association (APA)
Thiraphatthanavong, Paphaphat& Wattanathorn, Jintanaporn& Muchimapura, Supaporn& Thukham-mee, Wipawee& Wannanon, Panakaporn& Tong-Un, Terdthai…[et al.]. 2014. Preventive Effect of Zea mays L. (Purple Waxy Corn) on Experimental Diabetic Cataract. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-477147
Modern Language Association (MLA)
Thiraphatthanavong, Paphaphat…[et al.]. Preventive Effect of Zea mays L. (Purple Waxy Corn) on Experimental Diabetic Cataract. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-477147
American Medical Association (AMA)
Thiraphatthanavong, Paphaphat& Wattanathorn, Jintanaporn& Muchimapura, Supaporn& Thukham-mee, Wipawee& Wannanon, Panakaporn& Tong-Un, Terdthai…[et al.]. Preventive Effect of Zea mays L. (Purple Waxy Corn) on Experimental Diabetic Cataract. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-477147
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477147