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Hypoglycemic Effect of Laminaria japonica Polysaccharide in a Type 2 Diabetes Mellitus Mouse Model
Joint Authors
Guo, Yunliang
Li, Xiaodan
Yu, Zhuqin
Long, Shaohua
Duan, Delin
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-30
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The aim is to investigate the hypoglycemic effect of Laminaria japonica polysaccharides (LJPS) on type 2 diabetes mellitus (T2DM) mice model.
60 healthy male mice have been used in the experiment.
T2DM animal mode was prepared by high fatty forage feeding and intraperitoneal injection with alloxan.
Diabetic mice were orally supplied with LJPS.
Then their blood was collected for various biomedical measurements of fasting blood glucose (FBG), serum insulin, and amylin.
Treatment with LJPS significantly reduced fasting blood glucose (P<0.05) and increased the levels of insulin and amylin in serum (P<0.05).
Overall, the study presented that LJPS can reverse several components of T2DM.
Therefore, LJPS may become a new oral candidate medicine for the treatment of diabetes.
American Psychological Association (APA)
Li, Xiaodan& Yu, Zhuqin& Long, Shaohua& Guo, Yunliang& Duan, Delin. 2012. Hypoglycemic Effect of Laminaria japonica Polysaccharide in a Type 2 Diabetes Mellitus Mouse Model. ISRN Endocrinology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-477150
Modern Language Association (MLA)
Li, Xiaodan…[et al.]. Hypoglycemic Effect of Laminaria japonica Polysaccharide in a Type 2 Diabetes Mellitus Mouse Model. ISRN Endocrinology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-477150
American Medical Association (AMA)
Li, Xiaodan& Yu, Zhuqin& Long, Shaohua& Guo, Yunliang& Duan, Delin. Hypoglycemic Effect of Laminaria japonica Polysaccharide in a Type 2 Diabetes Mellitus Mouse Model. ISRN Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-477150
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477150