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Vesicoureteral Reflux, Reflux Nephropathy, and End-Stage Renal Disease
Author
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-07-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To review the contribution of vesicoureteral reflux and reflux nephropathy to end-stage renal disease.
Data Source.
Published research articles and publicly available registries.
Results.
Vesicoureteral reflux (VUR) is commonly identified in pediatric patients and can be associated with reflux nephropathy (RN), chronic kidney disease (CKD), and rarely end-stage renal disease (ESRD).
Patients with reduced GFR, bilateral disease, grade V VUR, proteinuria, and hypertension are more likely to progress to CKD and ESRD.
Because progression to ESRD is rare in VUR and often requires many decades to develop, there are limited prospective, randomized, controlled trials available to direct therapy to prevent progression to ESRD.
Conclusions.
Identification of patients with increased risk of progression to CKD and ESRD should be the goal of clinical, biochemical, and radiological evaluation of patients with VUR.
Treatment of patients with VUR should be directed at preventing new renal injury and preserving renal function.
American Psychological Association (APA)
Brakeman, Paul. 2008. Vesicoureteral Reflux, Reflux Nephropathy, and End-Stage Renal Disease. Advances in Urology،Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-477261
Modern Language Association (MLA)
Brakeman, Paul. Vesicoureteral Reflux, Reflux Nephropathy, and End-Stage Renal Disease. Advances in Urology No. 2008 (2008), pp.1-7.
https://search.emarefa.net/detail/BIM-477261
American Medical Association (AMA)
Brakeman, Paul. Vesicoureteral Reflux, Reflux Nephropathy, and End-Stage Renal Disease. Advances in Urology. 2008. Vol. 2008, no. 2008, pp.1-7.
https://search.emarefa.net/detail/BIM-477261
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477261