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Fracture Incidence, Quality of Life, and Back Pain during 18-Months Treatment with Teriparatide in Greek Postmenopausal Women with Osteoporosis : Results from the European Forsteo Observational Study
Joint Authors
Polydorakis, A.
Karras, D.
Korelis, E.
Drossinos, V.
Aloumanis, K.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To evaluate fracture incidence, effects on health-related quality of life(QoL), back pain (BP) occurrence and treatment compliance in Greek post-menopausal osteoporotic women treated with teriparatide (TPTD) for up to 18 months, in a naturalistic setting.
Methods.
301 patients provided baseline information on demographic characteristics, fracture history, osteoporosis-related medication and risk factors.
During treatment, QoL and BP severity were evaluated.
Results.
Mean (SD) age was 69.5 (±8.5) years.
Fracture history was reported by 92.5% of patients.
Incidence of fractures (per 10,000 patients/years) ranged from 402 during 0–6 months of treatment, to 346 during 12–18 months.
All 5 dimensions of QoL showed improvement.
At baseline and 18 months, BP was reported by 93.2% and 64.2% of patients, respectively.
BP and limitation of activities were quantified as moderate or severe by 89.9% and 62.3% of patients at baseline versus 32.4% and 14.8% at 18 months.
Patients on treatment at 6, 12, 17, and 18 months were 92.6%, 88.3%, 79.6%, and 36.5%, respectively.
Conclusions.
In the Greek EFOS study cohort, patients prescribed TPTD were severely osteoporotic, with considerable health-related problems.
Significant improvements in QoL and BP together with low fracture rates and high compliance have been recorded during treatment.
American Psychological Association (APA)
Aloumanis, K.& Karras, D.& Drossinos, V.& Korelis, E.& Polydorakis, A.. 2011. Fracture Incidence, Quality of Life, and Back Pain during 18-Months Treatment with Teriparatide in Greek Postmenopausal Women with Osteoporosis : Results from the European Forsteo Observational Study. Journal of Osteoporosis،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-477402
Modern Language Association (MLA)
Aloumanis, K.…[et al.]. Fracture Incidence, Quality of Life, and Back Pain during 18-Months Treatment with Teriparatide in Greek Postmenopausal Women with Osteoporosis : Results from the European Forsteo Observational Study. Journal of Osteoporosis No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-477402
American Medical Association (AMA)
Aloumanis, K.& Karras, D.& Drossinos, V.& Korelis, E.& Polydorakis, A.. Fracture Incidence, Quality of Life, and Back Pain during 18-Months Treatment with Teriparatide in Greek Postmenopausal Women with Osteoporosis : Results from the European Forsteo Observational Study. Journal of Osteoporosis. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-477402
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477402