![](/images/graphics-bg.png)
Synthesis of 1,5-Benzodiazepine and Its Derivatives by Condensation Reaction Using H-MCM-22 as Catalyst
Joint Authors
Tomar, Radha
Majid, Sheikh Abdul
Khanday, Waheed Ahmad
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A simple and versatile method for the synthesis of 1,5-benzodiazepines is via condensation of o-phenylenediamines (OPDA) and ketones in the presence of catalytic amount of H-MCM-22 using acetonitrile as solvent at room temperature.
In all the cases, the reactions are highly selective and are completed within 1–3 h.
The method is applicable to both cyclic and acyclic ketones without significant differences.
The reaction proceeds efficiently under ambient conditions with good-to-excellent yields.
American Psychological Association (APA)
Majid, Sheikh Abdul& Khanday, Waheed Ahmad& Tomar, Radha. 2012. Synthesis of 1,5-Benzodiazepine and Its Derivatives by Condensation Reaction Using H-MCM-22 as Catalyst. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-477431
Modern Language Association (MLA)
Majid, Sheikh Abdul…[et al.]. Synthesis of 1,5-Benzodiazepine and Its Derivatives by Condensation Reaction Using H-MCM-22 as Catalyst. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-477431
American Medical Association (AMA)
Majid, Sheikh Abdul& Khanday, Waheed Ahmad& Tomar, Radha. Synthesis of 1,5-Benzodiazepine and Its Derivatives by Condensation Reaction Using H-MCM-22 as Catalyst. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-477431
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477431