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Serologic Investigations in Children with Inflammatory Bowel Disease and Food Allergy
Joint Authors
Koryciak-Komarska, Halina
Sieroń, Aleksander L.
Grzybowska-Chlebowczyk, Urszula
Kasznia-Kocot, Joanna
Auguściak-Duma, Aleksandra
Woś, Halina
Więcek, Sabina
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-12-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The aim of the study was the evaluation of frequency and titre of IgA ASCA and IgG ASCA and p-ANCA, c-ANCA in children with IBD and occurrence of ASCA antibodies in relation to coexistence of FA.
Patients and methods.
The study comprised 95 children at the ages of 2 to 18 years.
The diagnosis of IBD was established on the basis of Porto criteria.
Tests of blood serum were performed in all children: IgA and IgG ASCA, p-ANCA, c-ANCA using ELISA method.
Results.
IgE-dependent FA was found in 32.5% children with UC and in 21% with CD.
We did not observe any relation between the occurrence of FA and the frequency and ASCA titre.
p-ANCA were significantly more frequent in the group of children with UC.
The occurrence of ASCA antibodies was observed in 73.7% of children with CD, 17.5% with UC and almost 30% with allergic colitis.
Conclusions.
Patients with CD and the presence of ASCA revealed a significantly more frequent localization of lesions within the small bowel and a tendency towards older age.
We observed a connection between the occurrence of antibodies and the examined mutations of gene NOD2/CARD15.
American Psychological Association (APA)
Grzybowska-Chlebowczyk, Urszula& Woś, Halina& Sieroń, Aleksander L.& Więcek, Sabina& Auguściak-Duma, Aleksandra& Koryciak-Komarska, Halina…[et al.]. 2009. Serologic Investigations in Children with Inflammatory Bowel Disease and Food Allergy. Mediators of Inflammation،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-477524
Modern Language Association (MLA)
Grzybowska-Chlebowczyk, Urszula…[et al.]. Serologic Investigations in Children with Inflammatory Bowel Disease and Food Allergy. Mediators of Inflammation No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-477524
American Medical Association (AMA)
Grzybowska-Chlebowczyk, Urszula& Woś, Halina& Sieroń, Aleksander L.& Więcek, Sabina& Auguściak-Duma, Aleksandra& Koryciak-Komarska, Halina…[et al.]. Serologic Investigations in Children with Inflammatory Bowel Disease and Food Allergy. Mediators of Inflammation. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-477524
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477524