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Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic Tools
Joint Authors
Pesl, Martin
Lacampagne, Alain
Acimovic, Ivana
Vilotic, Aleksandra
Meli, Albano C.
Dvorak, Petr
Rotrekl, Vladimir
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-02
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Human pluripotent stem cells (hPSCs), namely, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with their ability of indefinite self-renewal and capability to differentiate into cell types derivatives of all three germ layers, represent a powerful research tool in developmental biology, for drug screening, disease modelling, and potentially cell replacement therapy.
Efficient differentiation protocols that would result in the cell type of our interest are needed for maximal exploitation of these cells.
In the present work, we aim at focusing on the protocols for differentiation of hPSCs into functional cardiomyocytes in vitro as well as achievements in the heart disease modelling and drug testing on the patient-specific iPSC-derived cardiomyocytes (iPSC-CMs).
American Psychological Association (APA)
Acimovic, Ivana& Vilotic, Aleksandra& Pesl, Martin& Lacampagne, Alain& Dvorak, Petr& Rotrekl, Vladimir…[et al.]. 2014. Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic Tools. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-477543
Modern Language Association (MLA)
Acimovic, Ivana…[et al.]. Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic Tools. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-477543
American Medical Association (AMA)
Acimovic, Ivana& Vilotic, Aleksandra& Pesl, Martin& Lacampagne, Alain& Dvorak, Petr& Rotrekl, Vladimir…[et al.]. Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic Tools. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-477543
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477543