Late Renal Allograft Rupture Associated with Cessation of Immunosuppression following Graft Failure
Joint Authors
al-Enazi, Hanan
Aloudah, Noura
Alsaad, Khaled O.
Askandarani, Sumayah
Altamimi, Abdulrahman
Source
Case Reports in Transplantation
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A 29-year-old man developed chronic allograft nephropathy 63 months after renal transplantation.
He became symptomatic with advanced chronic graft failure; his immunosuppressive medications were reduced and he was commenced on haemodialysis.
Two months following the withdrawal of immunosuppression, he presented with abdominal pain, haematuria, and a marked drop in haemoglobin.
The patient was taken to the operating room, where the renal allograft was found to be ruptured, and graft nephrectomy was subsequently performed.
Histological examination of the graft specimen showed severe haemorrhagic acute vascular cellular rejection in a background of marked chronic allograft vasculopathy.
Immunostaining for C4d showed diffuse, strong, linear circumferential staining of the peritubular capillaries, indicating a concurrent antibody-mediated rejection.
We report herein an unusual case of spontaneous renal allograft rupture that occurred long time after transplantation due to severe acute rejection following cessation of immunosuppressive medications for advanced chronic allograft failure.
To the best of our knowledge, the time interval between transplantation and the rupture of this allograft is the longest of those reported in the literature.
American Psychological Association (APA)
Askandarani, Sumayah& Aloudah, Noura& al-Enazi, Hanan& Alsaad, Khaled O.& Altamimi, Abdulrahman. 2011. Late Renal Allograft Rupture Associated with Cessation of Immunosuppression following Graft Failure. Case Reports in Transplantation،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-477551
Modern Language Association (MLA)
Askandarani, Sumayah…[et al.]. Late Renal Allograft Rupture Associated with Cessation of Immunosuppression following Graft Failure. Case Reports in Transplantation No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-477551
American Medical Association (AMA)
Askandarani, Sumayah& Aloudah, Noura& al-Enazi, Hanan& Alsaad, Khaled O.& Altamimi, Abdulrahman. Late Renal Allograft Rupture Associated with Cessation of Immunosuppression following Graft Failure. Case Reports in Transplantation. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-477551
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477551