Locally Advanced Pancreatic Head Cancer : Margin-Positive Resection or Bypass?
Joint Authors
Höppner, Jens
Makowiec, Frank
Wellner, Ulrich Friedrich
Bausch, Dirk
Keck, Tobias
Hopt, Ulrich Theodor
Sick, Olivia
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Pancreatic cancer is a highly aggressive disease with poor survival.
The only effective therapy offering long-term survival is complete surgical resection.
In the setting of nonmetastatic disease, locally advanced tumors constitute a technical challenge to the surgeon and may result in margin-positive resection margins.
Few studies have evaluated the implications of the latter in depth.
The aim of this study was to compare the margin-positive situation to palliative bypass procedures and margin-negative resections in terms of perioperative and long-term outcome.
By retrospective analysis of prospectively maintained data from 360 patients operated for pancreatic cancer at our institution, we provide evidence that margin-positive resection still yields a significant survival benefit over palliative bypass procedures.
At the same time, perioperative severe morbidity and mortality are not significantly increased.
Our observations suggest that pancreatic cancer should be resected whenever technically feasible, including, cases of locally advanced disease.
American Psychological Association (APA)
Wellner, Ulrich Friedrich& Makowiec, Frank& Bausch, Dirk& Höppner, Jens& Sick, Olivia& Hopt, Ulrich Theodor…[et al.]. 2012. Locally Advanced Pancreatic Head Cancer : Margin-Positive Resection or Bypass?. ISRN Surgery،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-477592
Modern Language Association (MLA)
Wellner, Ulrich Friedrich…[et al.]. Locally Advanced Pancreatic Head Cancer : Margin-Positive Resection or Bypass?. ISRN Surgery No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-477592
American Medical Association (AMA)
Wellner, Ulrich Friedrich& Makowiec, Frank& Bausch, Dirk& Höppner, Jens& Sick, Olivia& Hopt, Ulrich Theodor…[et al.]. Locally Advanced Pancreatic Head Cancer : Margin-Positive Resection or Bypass?. ISRN Surgery. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-477592
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477592