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Comparing the Neuropsychiatric Profile of Patients with Alzheimer Disease Who Present Spared versus Impaired Executive Functioning
Joint Authors
Manes, Facundo
Gleichgerrcht, Ezequiel
Torralva, Teresa
Chade, Anabel
Roca, María
Source
Current Gerontology and Geriatrics Research
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
A “dysexecutive” group of patients with Alzheimer disease (AD) has been previously identified, and these patients have been found to present higher frequency of psychiatric symptoms and more pronounced functional impact.
This study aimed at evaluating the frequency of neuropsychiatric symptoms in patients with early AD who present with impaired executive functioning.
Methods.
Thirty patients with early AD diagnosis were divided into a spared (SEF) and an impaired (IEF) executive functioning group according to their performance scores on neuropsychological tests.
Their closest relatives or caregivers completed the Cambridge behavioral inventory (CBI), which assesses behavioral symptoms grouped into 13 categories.
Results.
A significant difference was exclusively found between SEF and IEF in terms of the frequency of stereotypies and repetitive motor behavior (U=60.5, P=.024).
Conclusions.
The presence of stereotypies could be associated with a dysexecutive profile in AD patients.
These results shed light on the role of frontal circuitry in the expression of motor symptoms in AD and prompt for further research that will contribute to the differential diagnosis both of different subtypes of AD and other types of dementia.
American Psychological Association (APA)
Gleichgerrcht, Ezequiel& Chade, Anabel& Torralva, Teresa& Roca, María& Manes, Facundo. 2011. Comparing the Neuropsychiatric Profile of Patients with Alzheimer Disease Who Present Spared versus Impaired Executive Functioning. Current Gerontology and Geriatrics Research،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-477670
Modern Language Association (MLA)
Gleichgerrcht, Ezequiel…[et al.]. Comparing the Neuropsychiatric Profile of Patients with Alzheimer Disease Who Present Spared versus Impaired Executive Functioning. Current Gerontology and Geriatrics Research No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-477670
American Medical Association (AMA)
Gleichgerrcht, Ezequiel& Chade, Anabel& Torralva, Teresa& Roca, María& Manes, Facundo. Comparing the Neuropsychiatric Profile of Patients with Alzheimer Disease Who Present Spared versus Impaired Executive Functioning. Current Gerontology and Geriatrics Research. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-477670
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477670