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Late Type of Bronchial Response to Milk Ingestion Challenge : A Comparison of Open and Double-Blind Challenge
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-03
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
In some asthmatics the food allergy, for example, to milk, can participate in their bronchial complaints.
The role of food allergy should be confirmed definitively by food ingestion challenge performed by an open challenge with natural foods (OFICH) or by a double-blind placebo-controlled food challenge (DBPCFC).
Objectives.
To investigate the diagnostic value of these techniques for confirmation of a suspected milk allergy in bronchial asthma patients.
Methods.
In 54 asthmatics with a positive history and/or positive skin tests for milk the 54 OFICH, and DBPCFC, were performed in combination with spirometry.
Results.
The 54 patients developed 39 positive late asthmatic responses (LAR) and 15 negative asthmatic responses to OFICH and 40 positive LARs and 14 negative responses to DBPCFC.
The overall correlation between the OFICH and DBPCFC was statistically significant (P<0.01).
Conclusions.
This study has confirmed the existence of LAR to milk ingestion performed by OFICH and DBPCFC in combination with spirometry.
The results obtained by both the techniques did not differ significantly.
The OFICH with natural food combined with monitoring of objective parameter(s), such as spirometry, seems to be a suitable method for detection of the food allergy in asthmatics.
The DBPCFC can be performed as an additional check, if necessary.
American Psychological Association (APA)
Pelikan, Zdenek. 2011. Late Type of Bronchial Response to Milk Ingestion Challenge : A Comparison of Open and Double-Blind Challenge. Journal of Allergy،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-477782
Modern Language Association (MLA)
Pelikan, Zdenek. Late Type of Bronchial Response to Milk Ingestion Challenge : A Comparison of Open and Double-Blind Challenge. Journal of Allergy No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-477782
American Medical Association (AMA)
Pelikan, Zdenek. Late Type of Bronchial Response to Milk Ingestion Challenge : A Comparison of Open and Double-Blind Challenge. Journal of Allergy. 2011. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-477782
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477782