In Vitro α-Amylase Inhibitory Activity of the Leaves of Thespesia populnea
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-20
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
Postprandial hyperglycemia is a prime characteristic of diabetes mellitus and has been a focus in the therapy for diabetes.
One of the therapeutic approaches which involve decreasing hyperglycemia aims at inhibiting the enzyme α-amylase.
The leaves of T.
populnea were studied for the presence of amylase inhibitors.
The fractions obtained by successive fractionation using solvents of varying polarity were studied for the presence of primary and secondary metabolites.
The total phenolic content of the different fractions was determined by HPLC and was correlated with their amylase inhibitory potential.
Similarly, the protein content of the extracts was also estimated to understand the nature of the inhibitor present.
This study shows that the leaves of T.
populnea were effective in inhibiting α-amylase, thereby proving to be potential hyperglycemic agents.
American Psychological Association (APA)
Sangeetha, R.& Vedasree, N.. 2012. In Vitro α-Amylase Inhibitory Activity of the Leaves of Thespesia populnea. ISRN Pharmacology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-477798
Modern Language Association (MLA)
Sangeetha, R.& Vedasree, N.. In Vitro α-Amylase Inhibitory Activity of the Leaves of Thespesia populnea. ISRN Pharmacology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-477798
American Medical Association (AMA)
Sangeetha, R.& Vedasree, N.. In Vitro α-Amylase Inhibitory Activity of the Leaves of Thespesia populnea. ISRN Pharmacology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-477798
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477798