The Role of Thrombophilia in Pregnancy
Joint Authors
Battinelli, Elisabeth M.
Marshall, Ariela
Connors, Jean M.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Thrombotic disease is a major cause of peripartum morbidity and mortality worldwide.
Development of thrombosis in pregnancy is multifactorial due to the physiologic changes of pregnancy—which induce a relative hypercoagulable state—as well as physical changes leading to increased stasis and also the effects of both the inherited and the acquired thrombophilias.
In this review, we discuss the impact of each of these factors on the development of thrombosis as well as the evidence for the impact of pregnancy-associated thrombosis on pregnancy outcome.
We then discuss the use of both prophylactic and therapeutic anticoagulation during pregnancy and the puerperium.
We review the indications and dosing recommendations for administration of anticoagulation in a context of discussing the evidence including the lack of evidence and formal guidelines in this area.
We briefly address the role of the new oral anticoagulants in pregnancy and conclude that significant further research in women with thrombophilias and pregnancy-associated thrombosis may help clarify the management of this condition in the future.
American Psychological Association (APA)
Battinelli, Elisabeth M.& Marshall, Ariela& Connors, Jean M.. 2013. The Role of Thrombophilia in Pregnancy. Thrombosis،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-477885
Modern Language Association (MLA)
Battinelli, Elisabeth M.…[et al.]. The Role of Thrombophilia in Pregnancy. Thrombosis No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-477885
American Medical Association (AMA)
Battinelli, Elisabeth M.& Marshall, Ariela& Connors, Jean M.. The Role of Thrombophilia in Pregnancy. Thrombosis. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-477885
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477885