Synthesis and Characterization of Process-Related Impurities of Antihypertensive Drug Olmesartan Medoxomil
Joint Authors
Venakata Narayana, G.
Mukkanti, K.
Sankar, A.
Venkanna, G.
Madhusudhan, G.
Sampath Kumar, Y.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Olmesartan medoxomil (1) is the latest angiotensin receptor antagonist approved by the FDA for the treatment of hypertension.
During the process development of olmesartan medoxomil, three process-related impurities were observed along with the final API.
These impurities were identified as isopropyl olmesartan (12), dimedoxomil olmesartan (19), dibiphenyl olmesartan (17).
The present work describes the synthesis and characterization of all these three impurities.
American Psychological Association (APA)
Venkanna, G.& Madhusudhan, G.& Mukkanti, K.& Sankar, A.& Sampath Kumar, Y.& Venakata Narayana, G.. 2012. Synthesis and Characterization of Process-Related Impurities of Antihypertensive Drug Olmesartan Medoxomil. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-477888
Modern Language Association (MLA)
Venkanna, G.…[et al.]. Synthesis and Characterization of Process-Related Impurities of Antihypertensive Drug Olmesartan Medoxomil. Journal of Chemistry No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-477888
American Medical Association (AMA)
Venkanna, G.& Madhusudhan, G.& Mukkanti, K.& Sankar, A.& Sampath Kumar, Y.& Venakata Narayana, G.. Synthesis and Characterization of Process-Related Impurities of Antihypertensive Drug Olmesartan Medoxomil. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-477888
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-477888
